CMR quantification of infarct tissue heterogeneity and remote myocardial fibrotic burden during convalescent phase following acute myocardial infarction (MI) provided strong and complementary evidence of ventricular arrhythmogenicity from quantitative microvolt T-wave alternans testing (the NHLBI PROSPECT-CMR study)

نویسندگان

  • Bobby Heydari
  • Shuaib Abdullah
  • Evan Appelbaum
  • Damien Mandry
  • Ron Blankstein
  • Yucheng Chen
  • Jiazuo H Feng
  • Karl-Philipp Kienle
  • Elliott Antman
  • Heidi S Lumish
  • Sanjeev Francis
  • Henry Gewirtz
  • Udo Hoffmann
  • Daniel Forman
  • Lahn Fendelander
  • Roger Plaisted
  • Rob J van der Geest
  • Michael Jerosch-Herold
  • Raymond Kwong
چکیده

CMR quantification of infarct tissue heterogeneity and remote myocardial fibrotic burden during convalescent phase following acute myocardial infarction (MI) provided strong and complementary evidence of ventricular arrhythmogenicity from quantitative microvolt T-wave alternans testing (the NHLBI PROSPECT-CMR study) Bobby Heydari, Shuaib Abdullah, Evan Appelbaum, Damien Mandry, Ron Blankstein, Yucheng Chen, Jiazuo H Feng, Karl-Philipp Kienle, Elliott Antman, Heidi S Lumish, Sanjeev Francis, Henry Gewirtz, Udo Hoffmann, Daniel Forman, Lahn Fendelander, Roger Plaisted, Rob J van der Geest, Michael Jerosch-Herold, Raymond Kwong

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Serial quantification of myocardial infarction tissue heterogeneity during infarct healing by cardiac MRI provides strong characterization of left ventricular remodeling (the NHLBI PROSPECT-CMR Study)

Background Late gadolinium enhancement (LGE) with infarct tissue heterogeneity characterized by cardiac magnetic resonance imaging (CMR) has been shown to be associated with arrhythmogenic substrates and increased mortality. Preliminary data suggests that areas of heterogeneous signal intensity (SI) within an infarct may represent an admixture of myocardial fibrosis, ischemic cellular apoptosis...

متن کامل

Myocardial Extracellular Volume Estimation by CMR Predicts Functional Recovery Following Acute MI

OBJECTIVES In the setting of reperfused acute myocardial infarction (AMI), the authors sought to compare prediction of contractile recovery by infarct extracellular volume (ECV), as measured by T1-mapping cardiac magnetic resonance (CMR), with late gadolinium enhancement (LGE) transmural extent. BACKGROUND The transmural extent of myocardial infarction as assessed by LGE CMR is a strong predi...

متن کامل

Myocardial Infarct Size by CMR in Clinical Cardioprotection Studies

OBJECTIVES The aim of this study was to review randomized controlled trials (RCTs) using cardiac magnetic resonance (CMR) to assess myocardial infarct (MI) size in reperfused patients with ST-segment elevation myocardial infarction (STEMI). BACKGROUND There is limited guidance on the use of CMR in clinical cardioprotection RCTs in patients with STEMI treated by primary percutaneous coronary i...

متن کامل

Recovery of regional myocardial function and myocardial oedema following reperfused acute myocardial infarction

We investigated the relationship between myocardial oedema and recovery of regional myocardial function in patients with acute reperfused myocardial infarction (MI). Early after acute MI, oedema in the peri-infarct zone, as delineated by T2 weighted (T2w) cardiovascular magnetic resonance (CMR) imaging, demonstrated significantly reduced strain as compared to remote myocardium. The recovery of ...

متن کامل

In vivo chronic myocardial infarction characterization by spin locked cardiovascular magnetic resonance

BACKGROUND Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is frequently used to evaluate myocardial viability, estimate total infarct size and transmurality, but is not always straightforward is and contraindicated in patients with renal failure because of the risk of nephrogenic systemic fibrosis. T2- and T1-weighted CMR alone is however relatively insensitive to chroni...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2012